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Issue 48, 2010
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Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

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Abstract

Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.

Graphical abstract: Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

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Supplementary files

Article information


Submitted
23 Aug 2010
Accepted
29 Sep 2010
First published
29 Oct 2010

Chem. Commun., 2010,46, 9119-9121
Article type
Communication

Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

M. K. Patel, B. Vijayakrishnan, J. R. Koeppe, J. M. Chalker, K. J. Doores and B. G. Davis, Chem. Commun., 2010, 46, 9119
DOI: 10.1039/C0CC03420G

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