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Issue 36, 2010
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ATP-modulated ionic transport through synthetic nanochannels

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Abstract

Here, we demonstrate an anion controlled molecular gate based on synthetic ion channels modified with polyethyleneimine. For single conical nanochannels, addition of ATP leads to significant decrease in the rectified ion flux, representing the closure of the ionic gate. Complementary experiments performed with nanoporous membranes show that the flux of charged dye (NDS2−) through a cylindrical nanochannel array diminishes by the co-addition of ATP in the analyte solution.

Graphical abstract: ATP-modulated ionic transport through synthetic nanochannels

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Publication details

The article was received on 28 May 2010, accepted on 26 Jul 2010 and first published on 25 Aug 2010


Article type: Communication
DOI: 10.1039/C0CC01632B
Citation: Chem. Commun., 2010,46, 6690-6692

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    ATP-modulated ionic transport through synthetic nanochannels

    M. Ali, Q. H. Nguyen, R. Neumann and W. Ensinger, Chem. Commun., 2010, 46, 6690
    DOI: 10.1039/C0CC01632B

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