Jump to main content
Jump to site search

Issue 30, 2010
Previous Article Next Article

Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method

Author affiliations

Abstract

A highly practical, catalytic enantioselective 2°-alkyl addition to aldehydes and ketones was developed. Chiral phosphoramide ligand (1) with salt-free and solvent-free di(2°-alkyl)zinc reagents prepared from (2°-alkyl)MgCl was essential.

Graphical abstract: Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method

Back to tab navigation

Supplementary files

Additions and corrections

Article information


Submitted
09 May 2010
Accepted
03 Jun 2010
First published
29 Jun 2010

Chem. Commun., 2010,46, 5443-5445
Article type
Communication

Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method

M. Hatano, T. Mizuno and K. Ishihara, Chem. Commun., 2010, 46, 5443
DOI: 10.1039/C0CC01301C

Social activity

Search articles by author

Spotlight

Advertisements