Jump to main content
Jump to site search

Issue 30, 2010
Previous Article Next Article

Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method

Author affiliations

Abstract

A highly practical, catalytic enantioselective 2°-alkyl addition to aldehydes and ketones was developed. Chiral phosphoramide ligand (1) with salt-free and solvent-free di(2°-alkyl)zinc reagents prepared from (2°-alkyl)MgCl was essential.

Graphical abstract: Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method

Back to tab navigation

Supplementary files

Additions and corrections

Publication details

The article was received on 09 May 2010, accepted on 03 Jun 2010 and first published on 29 Jun 2010


Article type: Communication
DOI: 10.1039/C0CC01301C
Chem. Commun., 2010,46, 5443-5445

  •   Request permissions

    Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method

    M. Hatano, T. Mizuno and K. Ishihara, Chem. Commun., 2010, 46, 5443
    DOI: 10.1039/C0CC01301C

Search articles by author

Spotlight

Advertisements