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Issue 10, 2010
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A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation

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Abstract

We present a simple, automated method for high-throughput formation of droplet interface bilayers (DIBs) in a microfluidic device. We can form complex DIB networks that are able to fill predefined three dimensional architectures. Moreover, we demonstrate the flexibility of the system by using a variety of lipids including 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

Graphical abstract: A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation

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Publication details

The article was received on 26 Nov 2009, accepted on 05 Jan 2010 and first published on 25 Jan 2010


Article type: Communication
DOI: 10.1039/B924897H
Citation: Chem. Commun., 2010,46, 1620-1622
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    A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation

    C. E. Stanley, K. S. Elvira, X. Z. Niu, A. D. Gee, O. Ces, J. B. Edel and A. J. deMello, Chem. Commun., 2010, 46, 1620
    DOI: 10.1039/B924897H

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