Issue 10, 2010
From the journal:

Chemical Communications

Quantitative, reagentless, single-step electrochemical detection of anti-DNA antibodies directly in blood serum†

Francesco Ricci,*a   Gianluca Adornetto,a   Danila Moscone,a   Kevin W. Plaxcob  and  Giuseppe Palleschia  

* Corresponding authors

a University of Rome Tor Vergata, Dipartimento di Scienze e Tecnologie Chimiche, Via della Ricerca Scientifica, Rome, Italy

b Department of Chemistry and Biochemistry, University of California, Santa Barbara, California, USA

Abstract

Here we demonstrate the use of redox labeled double- and single-stranded oligonucleotides as recognition probes for the reagentless, single-step, electrochemical detection of anti-DNA antibodies directly in blood serum.

Graphical abstract: Quantitative, reagentless, single-step electrochemical detection of anti-DNA antibodies directly in blood serum

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Article information

DOI
https://doi.org/10.1039/B922595A
Article type
Communication
Submitted
28 Oct 2009
Accepted
27 Nov 2009
First published
08 Jan 2010

Chem. Commun., 2010,46, 1742-1744

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Quantitative, reagentless, single-step electrochemical detection of anti-DNA antibodies directly in blood serum

F. Ricci, G. Adornetto, D. Moscone, K. W. Plaxco and G. Palleschi, Chem. Commun., 2010, 46, 1742 DOI: 10.1039/B922595A

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