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Issue 46, 2010
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Tetrasubstituted furans by PdII/CuI-cocatalyzed three-component domino reactions of 2-(1-alkynyl)-2-alken-1-ones, nucleophiles and diaryliodonium salts

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Abstract

A novel Pd(OAc)2/CuI-cocatalyzed three-component reaction of 2-(1-alkynyl)-2-alken-1-ones, nucleophiles and diaryliodonium salts has been developed. The procedure allows the synthesis of tetrasubstituted furans in good to high yields under mild conditions.

Graphical abstract: Tetrasubstituted furans by PdII/CuI-cocatalyzed three-component domino reactions of 2-(1-alkynyl)-2-alken-1-ones, nucleophiles and diaryliodonium salts

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Article information


Submitted
24 Aug 2010
Accepted
21 Sep 2010
First published
18 Oct 2010

Chem. Commun., 2010,46, 8839-8841
Article type
Communication

Tetrasubstituted furans by PdII/CuI-cocatalyzed three-component domino reactions of 2-(1-alkynyl)-2-alken-1-ones, nucleophiles and diaryliodonium salts

W. Li and J. Zhang, Chem. Commun., 2010, 46, 8839
DOI: 10.1039/C0CC03450A

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