Issue 40, 2010
From the journal:

Chemical Communications

NIR-enhanced drug release from porous Au/SiO2nanoparticles†

Clara Yagüe,a   Manuel Arruebo*a  and  Jesus Santamaria*ab  

* Corresponding authors

a Institute of Nanoscience of Aragón, University of Zaragoza, 50018 Zaragoza, Spain

b Networking Biomedical Research Center of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Maria de Luna, 11, 50018 Zaragoza, Spain
E-mail: Jesus.Santamaria@unizar.es

Abstract

The ability of core/shell SiO2/Au nanoparticles (NPs) to heat upon being exposed to near-infrared (NIR) radiation is well known. In this work we have modified the synthesis procedure to obtain a mesoporous SiO2 core and a porous Au shell that allows drugs to be loaded within the core porous space. The release of a model drug (ibuprofen) upon NIR activation is demonstrated.

Graphical abstract: NIR-enhanced drug release from porous Au/SiO2 nanoparticles

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Article information

DOI
https://doi.org/10.1039/C0CC01897J
Article type
Communication
Submitted
15 Jun 2010
Accepted
20 Aug 2010
First published
09 Sep 2010

Chem. Commun., 2010,46, 7513-7515

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NIR-enhanced drug release from porous Au/SiO2 nanoparticles

C. Yagüe, M. Arruebo and J. Santamaria, Chem. Commun., 2010, 46, 7513 DOI: 10.1039/C0CC01897J

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