Issue 37, 2010

Ortho-directed functionalization of arenes using magnesate bases

Abstract

Ortho-directed functionalisation of arenes using lithium alkylmagnesate bases were achieved, demonstrating the potential use of arylmagnesates as suitable arylanions, without a further transmetallation step, for challenging functionalizations such as fluorination, hydroxylation, arylation, vinylation and alkylation through epoxide ring-opening.

Graphical abstract: Ortho-directed functionalization of arenes using magnesate bases

Supplementary files

Article information

Article type
Communication
Submitted
03 Jun 2010
Accepted
13 Jul 2010
First published
26 Aug 2010

Chem. Commun., 2010,46, 7043-7045

Ortho-directed functionalization of arenes using magnesate bases

E. Bellamy, O. Bayh, C. Hoarau, F. Trécourt, G. Quéguiner and F. Marsais, Chem. Commun., 2010, 46, 7043 DOI: 10.1039/C0CC01731K

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