Issue 30, 2010

Stereochemistry of 4-hydroxyproline affects the conformation of conopeptides

Abstract

The cis/trans isomerization of 4-hydroxyproline is shown to remarkably affect the conformation of conopeptides with or without disulfide bonds.

Graphical abstract: Stereochemistry of 4-hydroxyproline affects the conformation of conopeptides

Supplementary files

Article information

Article type
Communication
Submitted
02 Mar 2010
Accepted
31 Mar 2010
First published
29 Apr 2010

Chem. Commun., 2010,46, 5467-5469

Stereochemistry of 4-hydroxyproline affects the conformation of conopeptides

J. Xu, Y. Wang, B. Zhang, B. Wang and W. Du, Chem. Commun., 2010, 46, 5467 DOI: 10.1039/C0CC00075B

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