Issue 23, 2010
From the journal:

Chemical Communications

Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl†

Tobias D. Blümke,a   Fabian M. Pillera  and  Paul Knochel*a  

* Corresponding authors

a Department Chemie, Ludwig-Maximilians-Universität, München, Butenandtstr. 5-13, Haus F, 81377 München, Germany
E-mail: Paul.Knochel@cup.uni-muenchen.de
Fax: +49-89-2180-77680
Tel: +49-89-2180-77681

Abstract

Alkyl bromides bearing various functional groups are smoothly converted to functionalized alkylzinc reagents by the direct insertion of magnesium in the presence of LiCl and ZnCl2.

Graphical abstract: Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl

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Article information

DOI
https://doi.org/10.1039/C001845G
Article type
Communication
Submitted
27 Jan 2010
Accepted
22 Mar 2010
First published
09 Apr 2010

Chem. Commun., 2010,46, 4082-4084

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Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl

T. D. Blümke, F. M. Piller and P. Knochel, Chem. Commun., 2010, 46, 4082 DOI: 10.1039/C001845G

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