Issue 12, 2010

Concise total synthesis of naamine G and naamidine H

Abstract

Total syntheses of the cytotoxic Leucetta-derived 2-aminoimidazoles, naamine G and naamidine H, have been accomplished using a position selective metalationbenzylation sequence with a 4,5-diiodoimidazole derivative.

Graphical abstract: Concise total synthesis of naamine G and naamidine H

Supplementary files

Article information

Article type
Communication
Submitted
14 Dec 2009
Accepted
22 Jan 2010
First published
09 Feb 2010

Chem. Commun., 2010,46, 2148-2150

Concise total synthesis of naamine G and naamidine H

P. B. Koswatta and C. J. Lovely, Chem. Commun., 2010, 46, 2148 DOI: 10.1039/B926285G

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