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Issue 15, 2010
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Iterative strategies for the synthesis of deoxypropionates

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Abstract

This feature article gives an overview of iterative synthetic methods for the construction of deoxypropionates, an important class of polyketides. The catalytic and non-catalytic methodologies discussed are based on highly stereoselective reactions which can be carried out in an iterative fashion. Non-catalytic methods are described first, followed by state of the art catalytic iterative protocols. The application of the iterative methods in the synthesis of natural products is discussed as well.

Graphical abstract: Iterative strategies for the synthesis of deoxypropionates

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Publication details

The article was received on 14 Dec 2009, accepted on 24 Feb 2010 and first published on 09 Mar 2010


Article type: Feature Article
DOI: 10.1039/B926265B
Chem. Commun., 2010,46, 2535-2547

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    Iterative strategies for the synthesis of deoxypropionates

    B. ter Horst, B. L. Feringa and A. J. Minnaard, Chem. Commun., 2010, 46, 2535
    DOI: 10.1039/B926265B

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