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Issue 15, 2010
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Iterative strategies for the synthesis of deoxypropionates

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Abstract

This feature article gives an overview of iterative synthetic methods for the construction of deoxypropionates, an important class of polyketides. The catalytic and non-catalytic methodologies discussed are based on highly stereoselective reactions which can be carried out in an iterative fashion. Non-catalytic methods are described first, followed by state of the art catalytic iterative protocols. The application of the iterative methods in the synthesis of natural products is discussed as well.

Graphical abstract: Iterative strategies for the synthesis of deoxypropionates

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Article information


Submitted
14 Dec 2009
Accepted
24 Feb 2010
First published
09 Mar 2010

Chem. Commun., 2010,46, 2535-2547
Article type
Feature Article

Iterative strategies for the synthesis of deoxypropionates

B. ter Horst, B. L. Feringa and A. J. Minnaard, Chem. Commun., 2010, 46, 2535
DOI: 10.1039/B926265B

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