Issue 13, 2010
From the journal:

Chemical Communications

In situazide formation and “click” reaction of nile red with DNA as an alternative postsynthetic route†

Christoph Beyera  and  Hans-Achim Wagenknechta  

a Institute for Organic Chemistry, University of Regensburg, 93040 Regensburg, Germany
E-mail: achim.wagenknecht@chemie.uni-regensburg,de
Fax: +49 941 943 4802

Abstract

Oligonucleotides that contain a 5-iodo-2′-deoxyuridine in the sequence can be applied for a postsynthetic “click”-type modification with ethynyl-modified nile red as a fluorescent label by in situ formation of the intermediate azide.

Graphical abstract: In situ azide formation and “click” reaction of nile red with DNA as an alternative postsynthetic route

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Article information

DOI
https://doi.org/10.1039/B924471A
Article type
Communication
Submitted
23 Nov 2009
Accepted
22 Dec 2009
First published
18 Jan 2010

Chem. Commun., 2010,46, 2230-2231

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In situ azide formation and “click” reaction of nile red with DNA as an alternative postsynthetic route

C. Beyer and H. Wagenknecht, Chem. Commun., 2010, 46, 2230 DOI: 10.1039/B924471A

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