Issue 12, 2010
From the journal:

Chemical Communications

Transfer of two-dimensional patterns of human umbilical vein endothelial cells into fibrin gels to facilitate vessel formation†

Takeaki Kawashima,a   Takeshi Yokoi,a   Hirokazu Kaji*ab  and  Matsuhiko Nishizawa*ab  

* Corresponding authors

a Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01, Aramaki, Aoba-ku, Sendai 980-8579, Japan
E-mail: kaji@biomems.mech.tohoku.ac.jp, nishizawa@biomems.mech.tohoku.ac.jp

b JST, CREST, Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan

Abstract

Two-dimensional cell patterns prepared on substrate surfaces by an electrochemical-based biolithography method have been transferred into fibrin gels prepared in situ. Line patterns of human umbilical vein endothelial cells (HUVECs) in the gel that was strained after the transfer formed a linear vessel-like structure within 8 days.

Graphical abstract: Transfer of two-dimensional patterns of human umbilical vein endothelial cells into fibrin gels to facilitate vessel formation

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Article information

DOI
https://doi.org/10.1039/B924397F
Article type
Communication
Submitted
20 Nov 2009
Accepted
29 Jan 2010
First published
15 Feb 2010

Chem. Commun., 2010,46, 2070-2072

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Transfer of two-dimensional patterns of human umbilical vein endothelial cells into fibrin gels to facilitate vessel formation

T. Kawashima, T. Yokoi, H. Kaji and M. Nishizawa, Chem. Commun., 2010, 46, 2070 DOI: 10.1039/B924397F

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