Issue 6, 2010
From the journal:

Chemical Communications

Practical copper(i)-catalysed amidation of aldehydes†

Joyce Wei Wei Chang,a   Thi My Uyen Ton,a   Stefani Tania,a   Paul C. Taylor*b  and  Philip Wai Hong Chan*a  

* Corresponding authors

a Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371
E-mail: waihong@ntu.edu.sg
Fax: 65 6791 1961
Tel: 65 6316 8760

b Department of Chemistry, University of Warwick, Coventry, UK

Abstract

The direct synthesis of amides by insertion into the C–H bond of aldehydes is shown to be a practical procedure through application of cheap, readily available catalysts generated in situ from copper(I) halides and pyridine.

Graphical abstract: Practical copper(i)-catalysed amidation of aldehydes

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Article information

DOI
https://doi.org/10.1039/B918588G
Article type
Communication
Submitted
08 Sep 2009
Accepted
16 Nov 2009
First published
04 Dec 2009

Chem. Commun., 2010,46, 922-924

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Practical copper(I)-catalysed amidation of aldehydes

J. W. W. Chang, T. M. U. Ton, S. Tania, P. C. Taylor and P. W. H. Chan, Chem. Commun., 2010, 46, 922 DOI: 10.1039/B918588G

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