Issue 3, 2010
From the journal:

Chemical Communications

Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media†

José Alemán,*a   Virginia del Solarb  and  Carmen Navarro-Ranninger*b  

* Corresponding authors

a Departamento de Química Orgánica (C-I), Universidad Autónoma de Madrid, 28049-Madrid, Spain

b Departamento de Química Inorgánica (C-VIII) Universidad Autónoma de Madrid, Cantoblanco, 28049-Madrid, Spain
E-mail: jose.aleman@uam.es, carmen.navarro@uam.es
Fax: (+) (0034) 914974833

Abstract

An efficient cyclization of alkyne-acids to enol-lactones catalyzed by anticancer platinum(II) and platinum(IV) compounds is described. These compounds are not only DNA-binding complexes; they can also catalyze reactions in solvents such as acetone, methanol, water or blood plasma.

Graphical abstract: Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

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Article information

DOI
https://doi.org/10.1039/B917758B
Article type
Communication
Submitted
28 Aug 2009
Accepted
21 Oct 2009
First published
11 Nov 2009

Chem. Commun., 2010,46, 454-456

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Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

J. Alemán, V. del Solar and C. Navarro-Ranninger, Chem. Commun., 2010, 46, 454 DOI: 10.1039/B917758B

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