A novel dipeptidomimetic containing a cyclic threonine†
Abstract
An efficient and simple two-step procedure for the formation of hydroxy-Freidinger lactams is presented. The methodology allows
* Corresponding authors
a
Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain
E-mail:
frank.sicherl@contractors.roche.com, albericio@irbbarcelona.org
Fax: +34 93 4037126
Tel: +34 93 4037088
b CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain
c Department of Organic Chemistry, University of Barcelona, Martí i Franqués 1, 08028-Barcelona, Spain
An efficient and simple two-step procedure for the formation of hydroxy-Freidinger lactams is presented. The methodology allows
F. Sicherl, T. Cupido and F. Albericio, Chem. Commun., 2010, 46, 1266 DOI: 10.1039/B915220B
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