Issue 5, 2010
From the journal:

Analytical Methods

SERRS-based detection ofdye-labeled DNA using positively-charged Agnanoparticles†

Ron Gill*a  and  Gerald W. Lucassena  

* Corresponding authors

a Philips Research, High Tech Campus, Eindhoven, The Netherlands
E-mail: ron.gill@philips.com
Fax: +31 40 2746321
Tel: +31 40 2747564

Abstract

Dye-labeled DNA at nanomolar concentration can be used to aggregate positively charged silver nanoparticles, giving detectable, dye-dependent, Raman spectra. The kinetics of the aggregation procedure can be enhanced by addition of molecules with multiple carboxylic groups, such as citrate or ethylene diamine tetra acetate (EDTA) ions.

Graphical abstract: SERRS-based detection of dye-labeled DNA using positively-charged Ag nanoparticles

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Article information

DOI
https://doi.org/10.1039/C0AY00190B
Article type
Communication
Submitted
21 Jan 2010
Accepted
31 Mar 2010
First published
15 Apr 2010

Anal. Methods, 2010,2, 445-447

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SERRS-based detection of dye-labeled DNA using positively-charged Ag nanoparticles

R. Gill and G. W. Lucassen, Anal. Methods, 2010, 2, 445 DOI: 10.1039/C0AY00190B

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