Issue 20, 2009

Highly enantioselective synthesis of angelmarin

Abstract

Angelmarin (1), a novel anti-cancer agent, was efficiently synthesized through a highly enantioselective epoxidation and a copper cyanide-mediated esterification of the hindered alcohol as the key steps in 53% overall yield.

Graphical abstract: Highly enantioselective synthesis of angelmarin

Supplementary files

Article information

Article type
Communication
Submitted
06 Jul 2009
Accepted
23 Jul 2009
First published
04 Aug 2009

Org. Biomol. Chem., 2009,7, 4173-4176

Highly enantioselective synthesis of angelmarin

H. Jiang and Y. Hamada, Org. Biomol. Chem., 2009, 7, 4173 DOI: 10.1039/B913400J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements