Issue 18, 2009

TTMPP: An efficient organocatalyst in the ring-opening of aziridines with silylated nucleophiles

Abstract

The ring-opening of N-tosylaziridines with silylated nucleophiles catalyzed by tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP) afforded the corresponding β-functionalized sulfonamides in excellent yield under mild reaction conditions.

Graphical abstract: TTMPP: An efficient organocatalyst in the ring-opening of aziridines with silylated nucleophiles

Supplementary files

Article information

Article type
Paper
Submitted
27 Apr 2009
Accepted
27 May 2009
First published
16 Jul 2009

Org. Biomol. Chem., 2009,7, 3792-3796

TTMPP: An efficient organocatalyst in the ring-opening of aziridines with silylated nucleophiles

S. Matsukawa and K. Tsukamoto, Org. Biomol. Chem., 2009, 7, 3792 DOI: 10.1039/B908322G

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