Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring
Abstract
Synthesis of a panel of iso(thio)urea-type ring-modified
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* Corresponding authors
a Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Profesor García González 1, Sevilla, (Spain)
b
York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, (UK)
E-mail:
davies@ysbl.york.ac.uk
c
Instituto de Investigaciones Químicas, CSIC–Universidad de Sevilla, Américo Vespucio 49, Isla de la Cartuja, Sevilla, (Spain)
E-mail:
jogarcia@iiq.csic.es
Synthesis of a panel of iso(thio)urea-type ring-modified
M. Aguilar-Moncayo, T. M. Gloster, J. P. Turkenburg, M. I. García-Moreno, C. Ortiz Mellet, G. J. Davies and J. M. García Fernández, Org. Biomol. Chem., 2009, 7, 2738 DOI: 10.1039/B906968B
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