Issue 16, 2009
From the journal:

Organic & Biomolecular Chemistry

A concise total synthesis of (±)-acutifolone A†

Ming-Tsang Hsieh,ac   Hsing-Jang Liu,*a   Tai Wei Lyb  and  Kak-Shan Shia*c  

* Corresponding authors

a Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013, R.O.C

b Axikin Pharmaceuticals, Inc., 10835 Road to the Cure, Suite 250, San Diego, CA 92121, USA

c Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County 35053, Taiwan, R.O.C
E-mail: ksshia@nhri.org.tw
Fax: +886-37-586456
Tel: +886-37-246166 ext:35709

Abstract

Starting from 4-methylcyclohexanone (7), a concise total synthesis of the pinguisane-type sesquiterpenoid acutifolone A, in racemic form, has been accomplished in 14 steps with an overall yield of 14.5%.

Graphical abstract: A concise total synthesis of (±)-acutifolone A

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B905910E
Article type
Paper
Submitted
24 Mar 2009
Accepted
21 May 2009
First published
19 Jun 2009

Org. Biomol. Chem., 2009,7, 3285-3290

Permissions

Request permissions

A concise total synthesis of (±)-acutifolone A

M. Hsieh, H. Liu, T. W. Ly and K. Shia, Org. Biomol. Chem., 2009, 7, 3285 DOI: 10.1039/B905910E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements