Radiolytic activation of a cytarabine prodrug possessing a 2-oxoalkyl group: one-electron reduction and cytotoxicity characteristics†
Abstract
An anti-tumour agent of
* Corresponding authors
a
Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Katsura Campus, Kyoto, Japan
E-mail:
tanabeka@scl.kyoto-u.ac.jp, nishimot@scl.kyoto-u.ac.jp
Fax: +81-75-383-2501
Tel: +81-75-383-2500
b Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan
c Nano-medicine Merger Education Unit, Kyoto University, Kyoto, Japan
An anti-tumour agent of
N. Hirata, Y. Fujisawa, K. Tanabe, H. Harada, M. Hiraoka and S. Nishimoto, Org. Biomol. Chem., 2009, 7, 651 DOI: 10.1039/B816194A
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