Issue 1, 2009

Aminoacid-derived mercaptoimidazoles

Abstract

Starting from suitably protected aminoacids, mercaptoimidazoles were synthesized either from the acid or including the amine nitrogen itself. A preliminary optimisation study led to efficient conditions for the obtention of the imidazole ring. These conditions are compatible with the presence of aminoacid or dipeptide scaffolds.

Graphical abstract: Aminoacid-derived mercaptoimidazoles

Supplementary files

Article information

Article type
Paper
Submitted
23 Jun 2008
Accepted
22 Sep 2008
First published
31 Oct 2008

Org. Biomol. Chem., 2009,7, 128-134

Aminoacid-derived mercaptoimidazoles

A. Crépin, N. Wattier, S. Petit, L. Bischoff, C. Fruit and F. Marsais, Org. Biomol. Chem., 2009, 7, 128 DOI: 10.1039/B810678A

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