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Issue 7, 2009
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Biocomputers: from test tubes to live cells

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Abstract

Biocomputers are man-made biological networks whose goal is to probe and control biological hosts—cells and organisms—in which they operate. Their key design features, informed by computer science and engineering, are programmability, modularity and versatility. While still a work in progress, biocomputers will eventually enable disease diagnosis and treatment with single-cell precision, lead to "designer" cell functions for biotechnology, and bring about a new generation of biological measurement tools. This review describes the intellectual foundation of the "biocomputer" concept as well as surveys the state of the art in the field.

Graphical abstract: Biocomputers: from test tubes to live cells

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Publication details

The article was received on 05 Feb 2009, accepted on 18 Mar 2009 and first published on 15 Apr 2009


Article type: Review Article
DOI: 10.1039/B902484K
Citation: Mol. BioSyst., 2009,5, 675-685

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    Biocomputers: from test tubes to live cells

    Y. Benenson, Mol. BioSyst., 2009, 5, 675
    DOI: 10.1039/B902484K

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