Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4′-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer
Abstract
Stability against
* Corresponding authors
a
Dept. of Neurogenetics AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
E-mail:
k.fluiter@amc.uva.nl
b Nucleic Acid Center, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark
Stability against
K. Fluiter, O. R. F. Mook, J. Vreijling, N. Langkjær, T. Højland, J. Wengel and F. Baas, Mol. BioSyst., 2009, 5, 838 DOI: 10.1039/B903922H
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