Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 45, 2009
Previous Article Next Article

The nanocomposites of SO3H-hollow-nanosphere and chiral amine for asymmetric aldol reaction

Author affiliations

Abstract

The nanocomposites formed by SO3H-hollow-nanospheres and chiral amines are highly efficient catalysts for the direct asymmetric aldol reaction of cyclohexanone and 4-nitrobenzaldehyde. The catalyst showed 91% yield with 96% ee under optimized reaction conditions. SO3H-hollow-nanospheres were synthesized by oxidation of thiol-hollow-nanospheres, which were fabricated through a one-pot co-condensation of 1,2-bis(trimethoxysilyl)ethane and 3-mercaptopropyltrimethoxysilane around F127 micelles in the presence of NaOAc. Chiral amines could be combined with SO3H-hollow-nanospheres through facile electrostatic interactions. The obtained nanocomposites showed a much higher reaction rate than the catalyst formed from the combination of chiral amine and SO3H-mesoporous-organosilica (ribbon shaped particles with particle size of tens of micrometres) in the direct asymmetric aldol reaction. This is mainly attributed to the hollow spherical morphology and nano-scale particle size (16–20 nm) of the SO3H-hollow-nanospheres.

Graphical abstract: The nanocomposites of SO3H-hollow-nanosphere and chiral amine for asymmetric aldol reaction

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 May 2009, accepted on 16 Jun 2009 and first published on 16 Jul 2009


Article type: Paper
DOI: 10.1039/B909002A
Citation: J. Mater. Chem., 2009,19, 8580-8588

  •   Request permissions

    The nanocomposites of SO3H-hollow-nanosphere and chiral amine for asymmetric aldol reaction

    J. Gao, J. Liu, S. Bai, P. Wang, H. Zhong, Q. Yang and C. Li, J. Mater. Chem., 2009, 19, 8580
    DOI: 10.1039/B909002A

Search articles by author

Spotlight

Advertisements