Issue 11, 2009
From the journal:

Green Chemistry

Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water†

Jin-Hong Lin,a   Cheng-Pan Zhanga  and  Ji-Chang Xiao*a  

* Corresponding authors

a Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai, P. R. China
E-mail: jchxiao@mail.sioc.ac.cn
Fax: (+86) 21-6416 6128

Abstract

Water was found to be a suitable reaction medium for the direct asymmetric aldol reaction of various cyclic ketones with aryl aldehydes catalyzed by a primary-tertiary diamine-Brønsted acid.

Graphical abstract: Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water

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Article information

DOI
https://doi.org/10.1039/B916583E
Article type
Communication
Submitted
11 Aug 2009
Accepted
01 Sep 2009
First published
11 Sep 2009

Green Chem., 2009,11, 1750-1753

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Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water

J. Lin, C. Zhang and J. Xiao, Green Chem., 2009, 11, 1750 DOI: 10.1039/B916583E

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