Issue 4, 2009
From the journal:

Green Chemistry

Long term continuous chemoenzymatic dynamic kinetic resolution of rac-1-phenylethanol using ionic liquids and supercritical carbon dioxide

Pedro Lozano,*a   Teresa De Diego,a   Corina Mira,a   Kimberley Montague,a   Michel Vaultierb  and  José L. Iborra*a  

* Corresponding authors

a Departamento de Bioquímica y Biología Molecular B e Inmunología, Facultad de Química, Universidad de Murcia, P.O. Box 4021, Murcia, Spain
E-mail: plozanor@um.es, jliborra@um.es
Fax: 34.968.36.41.48
Tel: 34.968.36.73.92

b Laboratoire de Chimie et Photonique Moléculaire, UMR CNRS 6510, Université de Rennes-1, Campus de Beaulieu, Av. Général Leclerc, Rennes, France
E-mail: Michel.Vaultier@univ-rennes1.fr
Fax: 33.2.99.28.69.55
Tel: 33.2.99.28.62.74

Abstract

The long term continuous dynamic kinetic resolution (DKR) of rac-phenylethanol in IL/scCO2 biphasic systems was carried out by simultaneously using immobilized lipase (Novozym 435) and acidic zeolite catalysts at 50 °C and 100 bar, providing good yields (up to 98.0%) for R-phenylethyl propionate with excellent enantioselectivity (up to 97.3% ee) and without any activity loss during 14 days of operation.

Graphical abstract: Long term continuous chemoenzymatic dynamic kinetic resolution of rac-1-phenylethanol using ionic liquids and supercritical carbon dioxide

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B821623A
Article type
Paper
Submitted
02 Dec 2008
Accepted
19 Jan 2009
First published
13 Feb 2009

Green Chem., 2009,11, 538-542

Permissions

Request permissions

Long term continuous chemoenzymatic dynamic kinetic resolution of rac-1-phenylethanol using ionic liquids and supercritical carbon dioxide

P. Lozano, T. De Diego, C. Mira, K. Montague, M. Vaultier and J. L. Iborra, Green Chem., 2009, 11, 538 DOI: 10.1039/B821623A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements