Issue 2, 2009

Synthesis of pyrazoles through catalyst-free cycloaddition of diazo compounds to alkynes

Abstract

The synthesis of pyrazoles via1,3-dipolar cycloaddition of diazo compounds to alkynes proceeds easily by heating. With α-diazocarbonyl substrates the reactions are conducted under solvent-free conditions affording the pyrazole products in high yields without any work up or purification.

Graphical abstract: Synthesis of pyrazoles through catalyst-free cycloaddition of diazo compounds to alkynes

Supplementary files

Article information

Article type
Communication
Submitted
24 Jul 2008
Accepted
25 Nov 2008
First published
09 Dec 2008

Green Chem., 2009,11, 156-159

Synthesis of pyrazoles through catalyst-free cycloaddition of diazo compounds to alkynes

D. Vuluga, J. Legros, B. Crousse and D. Bonnet-Delpon, Green Chem., 2009, 11, 156 DOI: 10.1039/B812242C

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