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Issue 42, 2009
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Decavanadate: a journey in a search of a role

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Abstract

Currently, efforts have been directed towards using decavanadate as a tool for the understanding of several biochemical processes such as muscle contraction, calcium homeostasis, in vivo changes of oxidative stress markers, mitochondrial oxygen consumption, mitochondrial membrane depolarization, actin polymerization and glucose uptake, among others. In addition, studies have been conducted in order to make vanadium available and safe for clinical use, for instance with decavanadate compounds that present interesting pharmacological properties, eventually useful for the treatment of diabetes. Here, recent contributions of decavanadate to the effects of vanadium in biological systems, not only in vitro, but also in vivo, are analysed

Graphical abstract: Decavanadate: a journey in a search of a role

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Publication details

The article was received on 16 Apr 2009, accepted on 08 Jul 2009 and first published on 13 Aug 2009


Article type: Perspective
DOI: 10.1039/B907581J
Dalton Trans., 2009, 9093-9100

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    Decavanadate: a journey in a search of a role

    M. Aureliano, Dalton Trans., 2009, 9093
    DOI: 10.1039/B907581J

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