Jump to main content
Jump to site search

Issue 33, 2009
Previous Article Next Article

Chiral diphosphinites derived from 2,2-biphosphole as a new class of stereodynamic ligands for enantioselective hydrogenation

Author affiliations

Abstract

New stereodynamic diphosphinites derived from 2,2′-biphosphole, were synthesised by introduction of a linker obtained from chiral diols between the two phosphorus atoms and used for catalytic hydrogenation through a dual chirality control induced by Rh-coordination. The application of these ligands in hydrogenation of dimethyl itaconate shows that the enantioselectivity strongly depends on steric and electronic properties of the chiral linker whereas the sense of enantioselection is determined by the configuration of these stereocentres. These stereodynamic diphosphinites induce higher enantioselectivities than the analogous stereodynamic diphosphanes derived from 2,2-biphosphole.

Graphical abstract: Chiral diphosphinites derived from 2,2-biphosphole as a new class of stereodynamic ligands for enantioselective hydrogenation

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 Jan 2009, accepted on 28 May 2009 and first published on 07 Jul 2009


Article type: Paper
DOI: 10.1039/B900829B
Citation: Dalton Trans., 2009,0, 6528-6535
  •   Request permissions

    Chiral diphosphinites derived from 2,2-biphosphole as a new class of stereodynamic ligands for enantioselective hydrogenation

    E. Robé, C. Hegedüs, J. Bakos, J. Daran and M. Gouygou, Dalton Trans., 2009, 0, 6528
    DOI: 10.1039/B900829B

Search articles by author

Spotlight

Advertisements