An enantiopure N,N,S scorpionate ligand derived from (+)-camphor

Abstract

Reductive S–S bond cleavage of a disulfide precursor 3 obtained from a pyridine-catalyzed Peterson-type reaction starting from camphorpyrazole 1, thionyl chloride and 2-methyl-2-(methyldithio)propionaldehyde yields 2,2′-bis(camphorpyrazol-1-yl)-2-methylpropane-2-thiol (HSⁱprbpm^3cam, 4); the first zinc complexes bearing this ligand exhibit κ³ coordination of the ligand.