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Issue 12, 2009
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Peptide-based fluorescent biosensors

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The use of fluorescent techniques in biological research is widespread. Many of the techniques rely on the use of fluorescent genetically-encoded tags (namely GFP and its different variants), but small molecules and nanoparticle-based approaches are being increasingly used. Peptides, owing to their modular nature, synthetic accessibility and biomolecular recognition potential, offer unique possibilities for the development of efficient and selective fluorescent sensors. In this tutorial review we present several of the strategies that have been used to develop fluorescent-based peptide sensors and discuss selected applications to biological problems.

Graphical abstract: Peptide-based fluorescent biosensors

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Publication details

The article was received on 29 Apr 2009 and first published on 11 Aug 2009

Article type: Tutorial Review
DOI: 10.1039/B908546G
Citation: Chem. Soc. Rev., 2009,38, 3348-3359

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    Peptide-based fluorescent biosensors

    E. Pazos, O. Vázquez, J. L. Mascareñas and M. Eugenio Vázquez, Chem. Soc. Rev., 2009, 38, 3348
    DOI: 10.1039/B908546G

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