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Issue 4, 2009
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Synthesis and applications of silicon-containing α-amino acids

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Abstract

Amino acids serve not only as monomers for proteins and enzymes but also as important players in signal transduction pathways. They belong to the abundant feedstock of the pharmaceutical, food science and agrochemical industries, and some are used as catalysts or ligand components. In recent years, non-proteogenic amino acids have taken on important roles. This tutorial review summarises the progress in the development of strategies to construct silicon-containing α-amino acid frameworks and the studies concerned with their structure and activity. It shall be of interest for the synthesis and biosciences communities.

Graphical abstract: Synthesis and applications of silicon-containing α-amino acids

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Publication details

The article was received on 24 Sep 2008 and first published on 16 Feb 2009


Article type: Tutorial Review
DOI: 10.1039/B816769A
Chem. Soc. Rev., 2009,38, 1002-1010

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    Synthesis and applications of silicon-containing α-amino acids

    M. Mortensen, R. Husmann, E. Veri and C. Bolm, Chem. Soc. Rev., 2009, 38, 1002
    DOI: 10.1039/B816769A

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