“Click” synthesis of isomeric compounds for assessing the efficiency of the bifurcated Br⋯NO2 synthon

Abstract

We report herein the extention of the azide–alkyne “click reaction” to crystal engineering and synthesize a collection of isomeric compounds with modular positioning of Br and NO₂ on a tricyclic template and crystal structural analyses of the derived isomers. It is quite remarkable to notice that none of the isomers displayed the bifurcated three-center NO₂⋯Br supramolecular synthon in their crystal structures