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Issue 47, 2009
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Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

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Abstract

A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (ϕem 12%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.

Graphical abstract: Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

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Publication details

The article was received on 29 Sep 2009, accepted on 20 Oct 2009 and first published on 02 Nov 2009


Article type: Communication
DOI: 10.1039/B920222F
Citation: Chem. Commun., 2009,0, 7321-7323
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    Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

    G. Law, R. Pal, L. O. Palsson, D. Parker and K. Wong, Chem. Commun., 2009, 0, 7321
    DOI: 10.1039/B920222F

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