Synthesis and validation of a probe to identify quorum sensing receptors
Abstract
The synthesis and evaluation of a ‘tag-free’ probe to isolate and identify receptors for N-acyl homoserine lactones is described.
* Corresponding authors
a
Department of Chemistry, Ben-Gurion University of the Negev, Be’er-Sheva 84105, Israel
E-mail:
meijler@bgu.ac.il
Fax: +972-8-6472751
Tel: +972-8-6472751
b
Department of Biomedical Engineering, The Kolff Institute, University Medical Center Groningen and the University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
E-mail:
b.p.krom@med.umcg.nl
Fax: +31-50-3633159
Tel: +31-50-3633160
c Department of Immunology and Microbial Sciences, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, USA
The synthesis and evaluation of a ‘tag-free’ probe to isolate and identify receptors for N-acyl homoserine lactones is described.
The article was received on 25 Aug 2009, accepted on 28 Sep 2009 and first published on 28 Oct 2009
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