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Issue 38, 2009
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Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

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Abstract

Treatment of N-allylacetamide with aryl halide in the presence of sodium t-butoxide and a palladium catalyst leads to arylative cyclisation to provide the corresponding benzyl-substituted oxazoline in high yield.

Graphical abstract: Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

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Publication details

The article was received on 30 Jun 2009, accepted on 21 Aug 2009 and first published on 03 Sep 2009


Article type: Communication
DOI: 10.1039/B912895F
Citation: Chem. Commun., 2009,0, 5754-5756
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    Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

    D. Fujino, S. Hayashi, H. Yorimitsu and K. Oshima, Chem. Commun., 2009, 0, 5754
    DOI: 10.1039/B912895F

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