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Issue 41, 2009
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A general electrochemical method for label-free screening of protein–small molecule interactions

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Abstract

Here we report a versatile method by which the interaction between a protein and a small molecule, and the disruption of that interaction by competition with other small molecules, can be monitored electrochemically directly in complex sample matrices.

Graphical abstract: A general electrochemical method for label-free screening of protein–small molecule interactions

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Supplementary files

Article information


Submitted
12 Jun 2009
Accepted
30 Jul 2009
First published
28 Aug 2009

Chem. Commun., 2009, 6222-6224
Article type
Communication

A general electrochemical method for label-free screening of protein–small molecule interactions

K. J. Cash, F. Ricci and K. W. Plaxco, Chem. Commun., 2009, 6222
DOI: 10.1039/B911558G

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