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Issue 27, 2009
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A new C–C bond forming annulation reaction leading to pH switchable heterocycles

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Abstract

A C–C bond forming reaction resulting from the α-addition of carbon based nucleophiles to N-bromoethyl phenanthridinium leads to the formation of 2,3-dihydro-12H-pyrrolo[1,2-f]phenanthridine-based derivatives which undergo reversible ring-opening/closing under pH control.

Graphical abstract: A new C–C bond forming annulation reaction leading to pH switchable heterocycles

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Article information


Submitted
17 Mar 2009
Accepted
01 May 2009
First published
28 May 2009

Chem. Commun., 2009, 4067-4069
Article type
Communication

A new C–C bond forming annulation reaction leading to pH switchable heterocycles

P. J. Kitson, A. D. C. Parenty, C. J. Richmond, D. Long and L. Cronin, Chem. Commun., 2009, 4067
DOI: 10.1039/B905383B

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