Issue 47, 2009

Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

Abstract

A homogeneous assay is reported using Ru(phen)2(dppz)2+ and a K+-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K+.

Graphical abstract: Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

Supplementary files

Article information

Article type
Communication
Submitted
04 Aug 2009
Accepted
06 Oct 2009
First published
22 Oct 2009

Chem. Commun., 2009, 7419-7421

Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

M. Sun Choi, M. Yoon, J. Baeg and J. Kim, Chem. Commun., 2009, 7419 DOI: 10.1039/B915994K

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