Issue 44, 2009
From the journal:

Chemical Communications

Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray†

Jing Zhang,a   Gwladys Pourceau,b   Albert Meyer,b   Sébastien Vidal,c   Jean-Pierre Praly,c   Eliane Souteyrand,a   Jean-Jacques Vasseur,b   François Morvan*b  and  Yann Chevolot*a  

* Corresponding authors

a INL UMR5270 CNRS Ecole Centrale de Lyon, 36 avenue G. de Collongue, 69134 Ecully cedex, France
E-mail: yann.chevolot@ec-lyon.fr
Fax: (+33) 472 18 6250
Tel: (+33) 472 18 6240

b IBMM UMR 5247 CNRS UM1 UM2, Université de Montpellier 2 Place Eugène Bataillon, F-34095 Montpellier Cedex 5, France
E-mail: morvan@univ-montp2.fr
Fax: (+33) 467 042 029
Tel: (+33) 467 144 961

c ICBMS – Laboratoire de Chimie Organique 2 (UMR 5246)CNRS Université Lyon 1, 43 Bd du 11 Novembre 1918, F-69622 Villeurbanne, France

Abstract

Two glycoconjugates bearing different DNA tags are mixed in solution with lectins; both interact with their specific lectin and the resulting complexes are sorted, according to their DNA sequences, at the surface of micro-reactors bearing the immobilised complementary DNA sequences.

Graphical abstract: Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

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Article information

DOI
https://doi.org/10.1039/B915132J
Article type
Communication
Submitted
24 Jul 2009
Accepted
17 Sep 2009
First published
30 Sep 2009

Chem. Commun., 2009, 6795-6797

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Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

J. Zhang, G. Pourceau, A. Meyer, S. Vidal, J. Praly, E. Souteyrand, J. Vasseur, F. Morvan and Y. Chevolot, Chem. Commun., 2009, 6795 DOI: 10.1039/B915132J

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