Issue 39, 2009
From the journal:

Chemical Communications

Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site†

Wee Han Anga  and  Stephen J. Lippard*a  

* Corresponding authors

a Department of Chemistry, Massachusetts Institute of Technology, Cambridge, USA
E-mail: lippard@mit.edu

Abstract

Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.

Graphical abstract: Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site

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Article information

DOI
https://doi.org/10.1039/B914843D
Article type
Communication
Submitted
22 Jul 2009
Accepted
26 Aug 2009
First published
08 Sep 2009

Chem. Commun., 2009, 5820-5822

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Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site

W. H. Ang and S. J. Lippard, Chem. Commun., 2009, 5820 DOI: 10.1039/B914843D

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