Issue 41, 2009
From the journal:

Chemical Communications

Efficient synthesis of dendrimersvia a thiol–yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs†

Gaojian Chen,a   Jatin Kumar,a   Andrew Gregorya  and  Martina H. Stenzel*a  

* Corresponding authors

a Centre for Advanced Macromolecular Design (CAMD), School of Chemical Science and Engineering, The University of New South Wales, Sydney, Australia
E-mail: M.Stenzel@unsw.edu.au
Tel: +61-293854344

Abstract

A combination of thiol–yne chemistry and esterification reactions were successfully applied for the preparation of dendrimers with an array of terminal functionalities via the divergent growth strategy; maximizing the number of reactive chain ends whilst minimizing the number of reaction steps required in the process.

Graphical abstract: Efficient synthesis of dendrimersvia a thiol–yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs

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Article information

DOI
https://doi.org/10.1039/B910340F
Article type
Communication
Submitted
27 May 2009
Accepted
21 Aug 2009
First published
04 Sep 2009

Chem. Commun., 2009, 6291-6293

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Efficient synthesis of dendrimersvia a thiol–yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs

G. Chen, J. Kumar, A. Gregory and M. H. Stenzel, Chem. Commun., 2009, 6291 DOI: 10.1039/B910340F

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