Issue 39, 2009
From the journal:

Chemical Communications

An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection†

Rongzhan Fu,a   Taihua Lia  and  Hyun Gyu Park*a  

* Corresponding authors

a Department of Chemical and Biomolecular Engineering, KAIST, Daejeon 305-701, Korea
E-mail: hgpark@kaist.ac.kr
Fax: +82 42 350 3910
Tel: +82 42 350 3932

Abstract

An ultrasensitive DNAzyme-based colorimetric DNA detection strategy was developed by utilizing gold nanoparticles modified with both peroxidase-mimicking DNAzymes and capture DNAs and magnetic nanoparticles modified with another capture DNAs, with a detection limit for a model Chlamydia gene of 50 fM.

Graphical abstract: An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection

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Article information

DOI
https://doi.org/10.1039/B907762F
Article type
Communication
Submitted
17 Apr 2009
Accepted
28 May 2009
First published
19 Jun 2009

Chem. Commun., 2009, 5838-5840

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An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection

R. Fu, T. Li and H. G. Park, Chem. Commun., 2009, 5838 DOI: 10.1039/B907762F

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