Issue 12, 2009

Zn(ii) complex for selective and rapid scission of protein backbone

Abstract

A ZnII complex with an aldehyde group hydrolyzed porcine pancreatic elastase under mild conditions, pH 8.0, 50 °C, by the Schiff base formation between the ZnII complex and the NH2 group in the protein, suggesting that a ZnII compound can be active toward peptide hydrolysis when it strongly binds to the substrate.

Graphical abstract: Zn(ii) complex for selective and rapid scission of protein backbone

Supplementary files

Article information

Article type
Communication
Submitted
14 Oct 2008
Accepted
19 Dec 2008
First published
29 Jan 2009

Chem. Commun., 2009, 1544-1546

Zn(II) complex for selective and rapid scission of protein backbone

M. Yashiro, Y. Kawakami, J. Taya, S. Arai and Y. Fujii, Chem. Commun., 2009, 1544 DOI: 10.1039/B818022A

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