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Issue 9, 2009
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Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules

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Abstract

Nanoshells are optically tunable core–shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.

Graphical abstract: Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules

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Article information


First published
24 Jul 2009

Analyst, 2009,134, 1745-1750
Article type
Minireview

Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules

C. S. Levin, J. Kundu, A. Barhoumi and N. J. Halas, Analyst, 2009, 134, 1745
DOI: 10.1039/B909080K

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