Issue 10, 2009
From the journal:

Analyst

Time-resolved lanthanide luminescence for lab-on-a-chip detection of biomarkers on cancerous tissues†

Bo Song,‡a   Venkataragavalu Sivagnanam,‡b   Caroline D. B. Vandevyver,*a   Ilkka Hemmilä,c   Hans-Anton Lehr,d   Martin A. M. Gijsb  and  Jean-Claude G. Bünzli*a  

* Corresponding authors

a Laboratory of Lanthanide Supramolecular Chemistry (LCSL), École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland
E-mail: jean-claude.bunzli@epfl.ch
Fax: +41 21 693 9815
Tel: +41 21 693 9824

b Laboratory of Microsystems, École Polytechnique Fédérale de Lausanne, Station 17, 1015 Lausanne, Switzerland

c PerkinElmer Human Health, Wallac Oy, P.O. Box 10, FIN-20101 Turku, Finland

d Institut Universitaire de Pathologie, Université de Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland

Abstract

PDMS-based microfluidic devices combined with lanthanide-based immunocomplexes have been successfully tested for the multiplex detection of biomarkers on cancerous tissues, revealing an enhanced sensitivity compared to classical organic dyes.

Graphical abstract: Time-resolved lanthanide luminescence for lab-on-a-chip detection of biomarkers on cancerous tissues

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Article information

DOI
https://doi.org/10.1039/B911301K
Article type
Communication
Submitted
09 Jun 2009
Accepted
24 Jun 2009
First published
29 Jun 2009

Analyst, 2009,134, 1991-1993

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Time-resolved lanthanide luminescence for lab-on-a-chip detection of biomarkers on cancerous tissues

B. Song, V. Sivagnanam, C. D. B. Vandevyver, I. Hemmilä, H. Lehr, M. A. M. Gijs and J. G. Bünzli, Analyst, 2009, 134, 1991 DOI: 10.1039/B911301K

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