Phenotypic heterogeneity within microbial populations at the single-cell level investigated by confocal Raman microspectroscopy†
Abstract
Single cells in genetically homogeneous microbial cultures exhibit marked phenotypic heterogeneity that is considered to bolster the fitness of the whole population. Heterogeneity on the single-cell level is typically masked in conventional studies of microbial populations, which rely on data averaged across thousands or millions of cells in a sample. Here we introduce
- This article is part of the themed collection: Optical Diagnosis